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Jun 29, 2026

Padres vs. Cubs Prediction, Odds, Probable Pitchers, Prop Bets for Monday, June 29

Padres vs. Cubs Prediction, Odds, Probable Pitchers, Prop Bets for Monday, June 29

Shota Imanaga and the Cubs are home favorites against the Padres.Ryan Gilbert|
Shota Imanaga and the Cubs are home favorites against the Padres.
Shota Imanaga and the Cubs are home favorites against the Padres. | Vincent Carchietta-Imagn Images

In this story:

San Diego PadresChicago Cubs

The Chicago Cubs got their mojo back on a road trip, sweeping the Mets in a four-game set and then taking two of three in Milwaukee. Meanwhile, the San Diego Padres lost their last two games against the Dodgers after winning four in a row.

The Cubs took two of three from the Padres in San Diego back in April.

Here are the odds, probable pitchers, and predictions for Padres vs. Cubs on Monday, June 29.

Padres vs. Cubs Odds, Run Line and Total

Odds via DraftKings Sportsbook

Run Line

  • Padres +1.5 (-136)
  • Cubs -1.5 (+113)

Moneyline

  • Padres +129
  • Cubs -156

Total

  • 11.5 (Over -115/Under -105)

Padres vs. Cubs Probable Pitchers

  • Padres: Griffin Canning (1-5, 7.38 ERA)
  • Cubs: Shota Imanaga (5-6, 4.40 ERA)

Griffin Canning is expected to get the nod for San Diego on Monday. He had a solid relief appearance two weeks ago, allowing one run on four hits in 4.1 innings, but then yielded four runs on as many hits while recording just two outs against the Braves last week.

Shota Imanaga got the win last time out, allowing four runs on as many hits (with three home runs) in 5.1 innings against the Mets. He had allowed just one run in 10.2 innings in his previous two starts, both against the Rockies.

Padres vs. Cubs How to Watch

  • Date: Monday, June 29
  • Time: 8:05 p.m. ET
  • Venue: Wrigley Field
  • How to Watch (TV): SDPA, MARQ
  • Padres record: 43-39
  • Cubs record: 46-38

Padres vs. Cubs Best MLB Prop Bets

Cubs Best MLB Prop Bet

  • Shota Imanaga UNDER 5.5 Hits Allowed (+107)

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