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Jul 02, 2026

He Helped Win the Giants' First Super Bowl. Then He Fought Cancer Twice.

He Helped Win the Giants' First Super Bowl. Then He Fought Cancer Twice.

The Giants tackle helped pave the way to the franchise's first championship — then fought off Hodgkin's disease twice before it forced him into early retirement.Paul Dottino|
Nov 6, 1988; East Rutherford, NJ, USA; FILE PHOTO; New York Giants offensive lineman Karl Nelson (63) on the sideline against the Dallas Cowboys at Giants Stadium during the 1988 season.
Nov 6, 1988; East Rutherford, NJ, USA; FILE PHOTO; New York Giants offensive lineman Karl Nelson (63) on the sideline against the Dallas Cowboys at Giants Stadium during the 1988 season. | RVR Photos-Imagn Images

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New York Giants

The broken foot that derailed New York Giants offensive tackle Karl Nelson's entire rookie season wound up being a small blip on his radar screen compared to the two bouts with Hodgkin’s disease that came later in his career.

The Giants, with Nelson anchoring their offensive line, won Super Bowl XXI — the first of the franchise's four championships and the one being celebrated this fall on its 40th anniversary.

New York was pleased to land the sturdy, 6-foot-6 tackle out of Iowa State in the third round of the 1983 NFL Draft.  

He excelled during his final year with the Cyclones, earning an All-Big Eight selection for the second straight season and gaining Academic All-America honors on his way to the East-West Shrine Game.

But a broken right foot suffered before his first pro season left him on the injured reserve list.

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